DriveCostCheck

2021 Mercedes-Benz GLS450 4matic

3.0L 6-cyl · 9-speed automatic · 4WD

HybridPremiumStandard Sport Utility Vehicle 4WD

Official EPA record #43170 from FuelEconomy.gov · data 2026-07-26 · every assumption below is yours to edit. How this is computed

Per month

$229.40

Per year

$2,753

Per mile

22.9¢/mi

5-year total

$13,765

sport utility body style — not this exact model
Notes & official EPA estimate
555 gal of fuel / yeargasoline @ $4.96/galAt $5.96/gal: $275.65/mo

Official FuelEconomy.gov estimate: $3,650/year — assumes 15,000 miles/year and EPA price assumptions. The figures above use your inputs instead.

Compare with another vehiclePrices: EPA national averages, Jul 24, 2026 — override anytime.
At 12,000 miles per year (55% city / 45% highway) with EPA national-average prices ($4.96/gal premium), this 2021 Mercedes-Benz GLS450 4matic costs about $229.40 per month in fuel — $2,753 per year, 22.9¢/mi, $13,765 over five years.Assumptions are editable below. Prices as of July 24, 2026 · EPA vehicle record #43170. EPA figures are laboratory estimates; real-world cost varies with driving conditions, weather, and where you buy energy.

Official EPA efficiency

MeasureValue
City MPG20
Highway MPG24
Combined MPG21

Official EPA estimates

EstimateValue
Official annual fuel cost (15,000 mi/yr)$3,650/yr
Tailpipe CO₂414 g/mi
EPA greenhouse gas score4/10
EPA smog rating (Federal Tier 3 Bin 50)6/10

Source: U.S. EPA / DOE FuelEconomy.gov, vehicle record #43170 (record updated 2021-04-26). Snapshot processed 2026-07-26; page data last changed 2021-04-26.

View this record on FuelEconomy.gov — includes owner-shared real-world MPG for this vehicle.

Related configurations

Same year, same family

Adjacent model years