2024 Mercedes-Benz E350 4matic

2.0L 4-cyl · 9-speed automatic · AWD

HybridPremiumMidsize Cars

Official EPA record #47579 from FuelEconomy.gov · data 2026-07-26 · every assumption below is yours to edit. How this is computed

Per month

$181.30

Per year

$2,176

Per mile

18.1¢/mi

5-year total

$10,880

sedan body style — not this exact model

Notes & official EPA estimate

438.6 gal of fuel / yeargasoline @ $4.96/galAt $5.96/gal: $217.86/mo

A mile road trip costs about $54.30 in energy.

Official FuelEconomy.gov estimate: $2,850/year — assumes 15,000 miles/year and EPA price assumptions. The figures above use your inputs instead.

Compare with another vehiclePrices: EPA national averages, Jul 24, 2026 — override anytime.

Cost per mile vs. its segment (2024 Midsize Cars, 48 vehicles, default assumptions)

This E350 4matic18.1¢/mi

Segment median11.8¢/mi

53% above the segment median — a measured energy-cost difference only.

At 12,000 miles per year (55% city / 45% highway) with EPA national-average prices ($4.96/gal premium), this 2024 Mercedes-Benz E350 4matic costs about $181.30 per month in fuel — $2,176 per year, 18.1¢/mi, $10,880 over five years.Assumptions are editable below. Prices as of July 24, 2026 · EPA vehicle record #47579. EPA figures are laboratory estimates; real-world cost varies with driving conditions, weather, and where you buy energy.

Mercedes-Benz E-Class: running costs for every model year →

Official EPA efficiency

Measure	Value
City MPG	24
Highway MPG	33
Combined MPG	27

Official EPA estimates

Estimate	Value
Official annual fuel cost (15,000 mi/yr)	$2,850/yr
Tailpipe CO₂	327 g/mi
EPA greenhouse gas score	5/10
EPA smog rating (Federal Tier 3 Bin 20)	8/10

Source: U.S. EPA / DOE FuelEconomy.gov, vehicle record #47579 (record updated 2024-07-30). Snapshot processed 2026-07-26; page data last changed 2024-07-30.

View this record on FuelEconomy.gov

Related configurations

Same year, same family

Adjacent model years