2026 Mercedes-Benz E350

2.0L 4-cyl · 9-speed automatic · RWD

HybridPremiumMidsize Cars

Official EPA record #49294 from FuelEconomy.gov · data 2026-07-26 · every assumption below is yours to edit. How this is computed

Per month

$176.76

Per year

$2,121

Per mile

17.7¢/mi

5-year total

$10,605

sedan body style — not this exact model

Notes & official EPA estimate

427.6 gal of fuel / yeargasoline @ $4.96/galAt $5.96/gal: $212.39/mo

A mile road trip costs about $53.10 in energy.

Official FuelEconomy.gov estimate: $2,750/year — assumes 15,000 miles/year and EPA price assumptions. The figures above use your inputs instead.

Compare with another vehiclePrices: EPA national averages, Jul 24, 2026 — override anytime.

Cost per mile vs. its segment (2026 Midsize Cars, 41 vehicles, default assumptions)

This E35017.7¢/mi

Segment median11.8¢/mi

50% above the segment median — a measured energy-cost difference only.

At 12,000 miles per year (55% city / 45% highway) with EPA national-average prices ($4.96/gal premium), this 2026 Mercedes-Benz E350 costs about $176.76 per month in fuel — $2,121 per year, 17.7¢/mi, $10,605 over five years.Assumptions are editable below. Prices as of July 24, 2026 · EPA vehicle record #49294. EPA figures are laboratory estimates; real-world cost varies with driving conditions, weather, and where you buy energy.

Mercedes-Benz E-Class: running costs for every model year →

Official EPA efficiency

Measure	Value
City MPG	25
Highway MPG	33
Combined MPG	28

Official EPA estimates

Estimate	Value
Official annual fuel cost (15,000 mi/yr)	$2,750/yr
Tailpipe CO₂	316 g/mi
EPA greenhouse gas score	5/10
EPA smog rating	not published

Source: U.S. EPA / DOE FuelEconomy.gov, vehicle record #49294 (record updated 2025-10-28). Snapshot processed 2026-07-26; page data last changed 2025-10-28.

View this record on FuelEconomy.gov

Related configurations

Same year, same family

Adjacent model years